Ligands assayed by host molecules including cyclophanes, crown e

Details Ligands assayed by host molecules including cyclophanes, crown e Ligands assayed by host molecules including cyclophanes, crown e

1979-09-25

1983-01-04

Marantz, Sidney

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436805, 436808, 436815, G01N 3122, G01N 3352

Patent

active

043670725

ABSTRACT:
Method for the determination of a component in a liquid which component is selected from ions, polar substances lipophilic substances, which comprises contacting a liquid sample containing said component with, and allowing same to act upon, a complex ligand or host molecule which is selective toward the component, said complex ligand or host molecule being bonded to a chromophore material, and measuring the change of extinction or the wavelength displacement of the resulting mixture as a measure of the initial content of said component; corresponding reagent test kits are also provided. The complex ligands or host molecules include cyclodextrins, cyclophanes, crown ethers, cryptands, podands valinomycin, gramacidin and monactin.

REFERENCES:
patent: 3789116 (1974-01-01), Kay
patent: 3950135 (1976-04-01), Whitesides
patent: 3992149 (1976-11-01), Wang
patent: 4005983 (1977-02-01), Dahms
patent: 4013414 (1977-03-01), Lavalle
patent: 4099918 (1978-07-01), Keand
J. Grandjean et al., Angew. Chem., Int. Ed. Engl., 17(11), 856-857 (1978).
J. Peter Dix et al., Agew. Chem., Int. Ed. Engl., 17(11), 857-859 (1978).
Chemical Abstracts, 88:145429y (1978).

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