Ligands and methods for augmenting B-cell proliferation

Details Ligands and methods for augmenting B-cell proliferation Ligands and methods for augmenting B-cell proliferation

1991-05-24

1993-01-26

Doll, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530350, 530351, 5303913, 5303917, 530866, 435188, C07K 1528, C07K 300

Patent

active

051823683

ABSTRACT:
A new B-cell receptor, Bp50, a 50 kilodalton polypeptide, that functions in B-cell proliferation is described. Ligands such as lymphokines, antibody molecules or the Fv fragments of antibody molecules that bind to Bp50 and augment the proliferation of activated B-cells can be used to regulate B-cell proliferation or differentiation.

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