Ligand specific to β 2 -glycoprotein I and use thereof

Details Ligand specific to β 2 -glycoprotein I and use thereof Ligand specific to β 2 -glycoprotein I and use thereof

2007-01-09

2007-01-09

Ceperley, Mary E. (Department: 1641)

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

C435S007500, C435S007920, C435S975000, C436S815000, C552S551000

Reexamination Certificate

active

10488688

ABSTRACT:
The cholesterol derivative, represented by the following formula (1):wherein R represents a C3–C23 saturated or unsaturated aliphatic hydrocarbon residue having an optional substituent, and, to the cholesterol backbone, —OH, —CHO, —COOH, —OOH, or an epoxy group may be added, specifically binds to β2-glycoprotein. By use of the derivative, β2-glycoprotein or a similar substance can be assayed in a very practical manner. Through the assay, a disease can be detected in a very practical manner.

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