Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Patent
1990-04-20
1992-04-21
Ceperley, Mary E.
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
436501, 436543, 436544, 436547, 530303, 530324, 530325, 530326, 530327, 530328, 530329, 530330, G01N 33532, G01N 33533, C07K 740
Patent
active
051067625
ABSTRACT:
Ligand-label conjugates which are an oligopeptide of 5 to 100 amino acid residues, bonded to a ligand or receptor, which contain a plurality of chemiluminescent or fluorescent labels and a plurality of polyoxoanions of sulfur or phosphorus are useful for immunoassays. Such conjugates are hydrophilic and exhibit very low nonspecific binding, thereby significantly increasing the signal to background ratio in immunoassays.
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M. Tal et al., Chem. Abst., vol. 103, No. 156719x (1985).
Bredehorst Reinhard
Kusterbeck Anne W.
Ligler Frances S.
Vogel Carl-Wilhelm
Wemhoff Gregory A.
Ceperley Mary E.
Georgetown University
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