Ligand for herpes simplex virus entry mediator and methods...

Details Ligand for herpes simplex virus entry mediator and methods... Ligand for herpes simplex virus entry mediator and methods...

2006-10-10

2006-10-10

Chan, Christina (Department: 1644)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S133100, C424S143100, C424S085400, C530S387100, C530S387300, C530S388200

Reexamination Certificate

active

07118742

ABSTRACT:
A novel polypeptide ligand, p30, or LIGHT, for herpes virus entry mediator, HVEM, is provided. LIGHT is useful for modulating immune responses and in inhibiting infection and/or subsequent proliferation by herpesvirus. HVEM fusion proteins are also provided. Methods for treating subjects with lymphoid cell disorders, tumors, autoimmune diseases, inflammatory disorders or those having or suspected of having a herpesvirus infection, utilizing p30 and the fusion proteins of the invention, are also provided.

REFERENCES:
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