Ligand for G-protein coupled receptor GPR72 and uses thereof

Details Ligand for G-protein coupled receptor GPR72 and uses thereof Ligand for G-protein coupled receptor GPR72 and uses thereof

2007-06-12

2010-11-02

Ulm, John D (Department: 1649)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007200, C435S007210, C436S501000

Reexamination Certificate

active

07824866

ABSTRACT:
The present invention relates to methods, reagents and kits for detecting of GPR72 polypeptide activity in a sample and identifying agents which modulate polypeptide activity. It further relates to antibodies raised against GPR72. It further relates to substances for preventing, treating and/or alleviating diseases or disorders characterized by dysregulation of GPR72 polypeptide signalling.

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Hansen et al., G Protein-Coupled Receptor 83 Overexpressed in Naive CD4+ CD25-− T Cells Leads to the Induction of Foxp3+ Regulatory T Cells In Vivo, Jul. 1, 2006, Journal of Immunology 177:209-215.
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