Ligand assay using interference modulation

Details Ligand assay using interference modulation Ligand assay using interference modulation

1991-05-29

1993-03-23

Nucker, Christine M.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

435 71, 435 792, 435 793, 435 794, 435 795, 436518, 436524, C12Q 100, G01N 3353, G01N 33566, G01N 33554

Patent

active

051963507

ABSTRACT:
An optical detection method for detecting specific ligands in an immunoassay is formed by diffracting a beam of light through slits formed in a mask and thererby forming an interference pattern. The diffracted light of one of the slits is distributed by an assay having a ligand which when reacted with anti-ligand changes the optical characteristics of the assay thereby changing the interference pattern in a concentration dependent manner.

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