LicB polypeptides from Streptococcus pneumoniae

Details LicB polypeptides from Streptococcus pneumoniae LicB polypeptides from Streptococcus pneumoniae

1998-02-17

1999-10-05

Duffy, Patricia A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

435183, 435220, 4241841, 4241851, 4241921, 4242441, C12N 910, A61K 3900, A61K 3909

Patent

active

059622954

ABSTRACT:
The invention provides licB polypeptides and polynucleotides encoding licB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing licB polypeptides to screen for antibacterial compounds.

REFERENCES:
GenBank Submission, Accession No. U32829, Fleischmann et al, Sep. 27, 1996.
Weiser, et al., "Decoration of Lipopolysaccharide With Phosphorylcholine: A Phase-Variable Characteristic of Haemophilus influenzae", Infection and Immunity, vol. 65, No. 3, pp. 943-950, (Mar., 1997).
Database EMBL, European Bioinformatics Institute, Accession No. AF036951, Jan. 5, 1998, Wieser J.N., et al., "Streptococcus pneumoniae choline kinase (pck) gene, complete cds."
Database PIR, European Bioinformatics Institute, Accession No. B33465, Dec. 20, 1989, Weiser J.N., et al., "lic-1 protein B-Haemophilus influenzae (strain RM7004)."

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