LHRH antagonists

Details LHRH antagonists LHRH antagonists

1991-01-30

1992-12-15

Cashion, Jr., Merrell C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Lutenizing hormone releasing factor ; related peptides

530318, 514900, 930110, 930130, 930320, C07K 720

Patent

active

051718359

ABSTRACT:
Disclosed herein are analogues of the luteinizing hormone-releasing hormone (LH-RH), which are potent antagonists of LH-RH. These peptides inhibit the release of gonadotropins from the pituitary in mammals, including humans and possess antitumor activity.
Formula I represents peptides which are within the scope of this invention:

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