LHRH antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

525 5411, 530313, 514800, A61K 3743, C07K 720, C08F28300

Patent

active

048001910

ABSTRACT:
The present invention deals with LHRH antagonists which possess improved water solubility and while having the high antagonist potency of the basic peptides, are free of the edematogenic effects. These compounds are highly potent in inhibiting the release of gonadotropins from the pituitary gland in mammals, including humans.
The compounds of this invention are represented by the formula

REFERENCES:
Chem. Abstr. vol. 82 (1975) 73465h.
Chem. Abstr. vol. 86 (1977) 5813c.

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