LH-RH antagonists having improved action

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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Details

530300, 530311, 530328, A61K 3800, A61K 3802, C07K 500, C07K 700

Patent

active

059424931

ABSTRACT:
New LH-RH antagonists are disclosed, in particular peptidomimetics and peptides modified in a side chain, their salts with pharmaceutically acceptable acids and a process for preparing these LH-RH antagonists and their salts. The disclosed peptides represent analogues of the luteinising hormone releasing hormone (LH-RH). The disclosed compounds have a high antagonistic power and are free of undesirable side effects, in particular edematogenic effects.

REFERENCES:
patent: 5300492 (1994-04-01), Haviv et al.

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