Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1982-01-20
1984-02-14
Phillips, Delbert K.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125LH, H61K 3700, C07C10352
Patent
active
044316356
ABSTRACT:
Disclosed herein are peptide analogs of the luteinizing hormone releasing hormone (LH-RH) which are potent antagonists of LHRH. The analogs differ in structure from LH-RH by having different amino acid residues at positions 1, 2 and 6, and optionally at positions 3 and 10. Methods for preparing and using these analogs are described.
REFERENCES:
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patent: 3933782 (1976-01-01), Yardley
patent: 4018726 (1977-06-01), Schally et al.
patent: 4124703 (1978-11-01), Dutta et al.
patent: 4253997 (1981-03-01), Sarantakis
patent: 4317815 (1982-03-01), Cory et al.
Coy David H.
Shally Andrew V.
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