Levulinic acid salt

Details Levulinic acid salt Levulinic acid salt

1978-10-02

1979-07-17

Rush, Raymond V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424251, C07D23995

Patent

active

041615956

ABSTRACT:
The invention concerns a levulinic acid addition salt of the antihypertensive agent 4-amino-6,7-dimethoxy-2-[4-(5-methylthio-1,3,4-oxadiazole-2-carbonyl]piper azin-1-yl)quinazoline in which the base to acid mole ratio is 1 to from 1.25-1.35. The salt is characterized in having improved water solubility and stability compared to the levulinate salt having a 1:1 ratio of base to acid.

REFERENCES:
patent: 4001238 (1977-01-01), Partyka et al.

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