Leustroducsin H, its preparation and its therapeutic use

Details Leustroducsin H, its preparation and its therapeutic use Leustroducsin H, its preparation and its therapeutic use

1994-04-08

1995-04-25

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

549222, A61K 31665, C07F 9655

Patent

active

054099129

ABSTRACT:
A new compound, which we have named Leustroducsin H, has formula (I): ##STR1## and pharmaceutically acceptable salts thereof. This compound may be prepared by hydrolysis of naturally occurring Leustroducsins and the compound may be used for the treatment or prophylaxis of thrombocytopenia.

REFERENCES:
patent: 5021406 (1991-06-01), Maeda et al.
patent: 5334587 (1994-08-01), Kohama et al.
Chemical Abstracts, vol. 119, No. 25, 20 Dec. 1993, Columbus, Ohio, US, Abstract No. 269174, Furuhama T. et al, "Manufacture of 2-pyranones with Streptomyces platensis for treatment of thrombocytopenia" of JP-A-93 213 758 (Sankyo Co., Japan), 24 Aug. 1993.

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