Leukotriene-B4 derivatives, process for their production and the

Details Leukotriene-B4 derivatives, process for their production and the Leukotriene-B4 derivatives, process for their production and the

1995-06-05

1997-03-25

Jordan, Charles T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546261, 546262, 546263, 546265, 546266, 546267, 546290, 546309, 546314, 546323, 546344, 546339, 546340, 562470, C07D21389

Patent

active

056146345

ABSTRACT:
Leukotriene-B.sub.4 analogs of formula I ##STR1## in which R.sup.1 means radical COOR.sup.2 with R.sup.2 meaning a hydrogen atom or a (C.sub.1 -C.sub.4)-alkyl group or R.sup.1 means radical CH.sub.2 OH,

REFERENCES:
patent: 5440044 (1995-08-01), Heindl et al.
"Asymmetric Synthesis of the Diastereoisomers of the Leukotriene B4 Antagonist," Burgos et al., Tetrahedron Letters, vol. 30 (38), Oct. 1989, pp. 5081-5084.
"Novel Molecules that Antagonize Leucotriene B.sub.4 Binding . . . ", Lin et al., Ann. N.Y. Acad. Sci., vol. 524, Apr, 9, 1988, pp. 196-200.
"Synthesis of Novel Antagonists of Leukotriene B4", Morris et al., Tetrahedron Ltrs., vol. 29(2), Jan. 1988, pp. 143-146.

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