Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1994-02-14
1996-09-03
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514571, 562461, 562464, A61K 3119, C07C 6304
Patent
active
055524419
ABSTRACT:
This invention provides certain 1,2,4,5 substituted benzene derivatives containing "acid" substituents derived from cyclic or heterocyclic moieties. These unique compounds are leukotriene B.sub.4 antagonists and formulations of these derivatives, and a method of using these derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.
REFERENCES:
patent: 4200577 (1980-04-01), Buckle et al.
patent: 4211791 (1980-07-01), Buckle et al.
patent: 4945099 (1990-07-01), Bollinger et al.
Buckle et al., J. Med. Chem 22 (2) 158-68 (1979).
Dillard Robert D.
Sawyer J. Scott
Sofia Michael J.
Benjamin Roger S.
Boone David E.
Eli Lilly and Company
Peabody John
Richter Johann
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