Leukotriene antagonists, processes for the preparation thereof,

Details Leukotriene antagonists, processes for the preparation thereof, Leukotriene antagonists, processes for the preparation thereof,

1988-07-22

1989-07-25

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514532, 514570, 514571, 514618, 560 11, 560 15, 560 17, 560 60, 562426, 562429, 562470, 564161, 564162, 564169, 564170, A61K 31215, C07C149273

Patent

active

048514403

ABSTRACT:
Leukotriene antagonists, processes for the preparation thereof, the use thereof for the treatment of diseases, and precursors.
Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and X have the indicated meanings, processes for the preparation of these compounds, the use thereof as pharmaceuticals, and pharmaceutical products based on these compounds are described. In addition, precursors for the preparation of compounds of the formula I are described.

REFERENCES:
patent: 3867434 (1975-02-01), Diamond
patent: 3894080 (1975-07-01), Diamond et al.
patent: 3993683 (1976-11-01), Nickl et al.
patent: 4785004 (1988-11-01), Von Sprecher et al.
Musser et al., Agents and Actions, vol. 18, pp. 332-341 (1986).
Gleason et al., Journal of Medicinal Chemistry, vol. 30, No. 6, pp. 959-961 (1987).

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