Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-12-21
1992-09-01
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514251, 514252, 514253, C07D25700, A61K 3141
Patent
active
051439310
ABSTRACT:
This invention relates to alkanoic acid compounds having phenyl and heteroarylthio substituents which are useful as leukotriene antagonists and pharmaceutical compositions containing such compounds. This invention also relates to methods of treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.
REFERENCES:
patent: 4069744 (1986-09-01), Young et al.
patent: 4666928 (1987-05-01), Young et al.
patent: 4717409 (1986-10-01), Young et al.
Derwent Patent Abstract 84-014267/03 of Japanese Patent Appln. 58206556A published Dec. 1, 1983.
Derwent Patent Abstract 85-026589/05 of European Patent Appln. 132366A published Jan. 30, 1985.
Chem. Abstract 96(17):143290n.
Chem. Abstract 94(9): 64755y.
Chemical Abstracts, vol. 101, No. 17, p. 718, Abstract 151857q (Oct. 22, 1984).
Patent Abstracts of Japan, vol. 9, No. 306 (C-317) (2029) Dec. 3, 1985.
Gleason John G.
Hall Ralph F.
Uzinskas Irene
Kanagy James M.
Lentz Edward T.
SmithKline Beecham Corporation
Springer David B.
Suter Stuart R.
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