Leukotriene antagonists, compositions and methods of use thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514419, 514562, 514568, 546253, 546252, 562426, 562431, C07D24704, A61K 3141, A61K 3119, C07F 5746

Patent

active

049905260

ABSTRACT:
Compounds having the formula: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis, and inhibitors of their biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory agents, anti-psoriatic agents, and cytoprotective agents.

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