Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1983-03-07
1985-11-12
Waltz, Thomas A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
260399, 2604025, 260404, 2604045, 514561, 514564, 514616, 514626, 514627, 562556, 562581, 564154, 564192, A61K 3120, C07C103187, C07C 5712, C07C 5713
Patent
active
045528934
ABSTRACT:
The compounds represented by the formula (I) ##STR1## wherein m is 0, 1 or 2; p is 9, 10, 11, 12 or 13; R.sub.1 is hydrogen, amino or ##STR2## R.sub.2 is hydroxyl, amino, --NHCH.sub.2 CO.sub.2 H, ##STR3## or --NHCH.sub.2 CONH.sub.2 ; and X is --CO.sub.2 H, --CH.sub.2 OH or ##STR4## with the proviso that when m is 0, R.sub.1 is hydrogen, or a pharmaceutically acceptable salt thereof have been found to be leukotriene antagonists and useful in the treatment of diseases in which leukotrienes are a factor, such as asthma.
REFERENCES:
patent: 2994662 (1961-08-01), Calhoun et al.
patent: 4061634 (1977-12-01), Mod et al.
patent: 4311645 (1982-01-01), Rosenberger
patent: 4461775 (1984-07-01), Stanley et al.
patent: 4469705 (1984-09-01), Stanley et al.
Gleason John G.
Hall Ralph F.
Ku Thomas W.
Foggio Richard D.
Lourie Alan D.
SmithKline Beckman Corporation
Waltz Thomas A.
LandOfFree
Leukotriene antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Leukotriene antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Leukotriene antagonists will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1880472