Leukotriene antagonists

Details Leukotriene antagonists Leukotriene antagonists

1984-11-13

1988-01-19

Siegel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514534, 514535, 514544, 514557, 514561, 514562, 514568, 514570, 560 9, 560 11, 560 12, 560 19, 560 45, 560 46, 560 55, 560 64, 560 65, 562426, 562429, 562430, 562432, 562442, 562452, 562453, 562465, 562473, 562474, C07C14940, C07C147107, C07C14367, C07C10100, C07C15100, C07C14711, C07C14713, C07C10172

Patent

active

047205059

ABSTRACT:
Compounds having the formula: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic and anti-inflammatory agents.

REFERENCES:
patent: 4667055 (1987-05-01), Gillard et al.
D. M. Bailey et al., Ann Rpts. Med. Chem, 17, 203 (1982).
B. Samuelsson, Science 220, 568 (1983).

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