Leukotriene antagonists

Details Leukotriene antagonists Leukotriene antagonists

1984-01-19

1986-11-18

Garner, Vivian

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

26050121, 424 44, 424 45, 514554, 514574, 514826, 514958, 562594, C07C14920, A61K 3119, A61K 31205

Patent

active

046235353

ABSTRACT:
The compounds represented by the following structural formula (I) ##STR1## wherein m and n are independently 1, 2 or 3; R.sub.1 is an C.sub.8 to C.sub.13 alkyl radical and pharmaceutically acceptable salts thereof have been found to be leukotriene antagonists and useful in the treatment of diseases in which leukotrienes are a factor, such as asthma.

REFERENCES:
patent: 2602816 (1952-07-01), Gregory et al.
patent: 3217004 (1965-10-01), Hechenbleikner et al.
patent: 3742031 (1973-06-01), Lafon
Yasuo Kishimoto et al, Yakugaku Zasshi, 73:447-50 (1958).
Kogo et al, Chemical Abstracts, 89:130417q (1978).

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