Leukotriene antagonists

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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514469, 514460, 514222, 548252, 548253, 548254, 549 9, 549 52, 549 58, 549 53, 549399, 549407, 549466, 549467, 549469, 549405, 549406, 549350, C07D30788, C07D31104

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active

046174079

ABSTRACT:
Compounds having the formula: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.

REFERENCES:
patent: 4237144 (1980-12-01), Cragoe, Jr.
patent: 4401669 (1983-08-01), Cragoe, Jr.
Chem. Abst.; 99; 212,252c.

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