Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-11-27
1984-04-10
Shippen, Michael L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424267, 424274, 424305, 424316, 424317, 424320, 424324, 2605011, 544176, 548540, 560124, 562506, 564190, C07C 69743, C07C103737, A61K 31215, A61K 3116
Patent
active
044420994
ABSTRACT:
A compound of the formula ##STR1## wherein n is an integer from 2 to 4; m is an integer from 3 to 5; R is OM, OR.sub.1 or NR.sub.2 R.sub.3 where M is a pharmaceutically acceptable cation;
R.sub.1, R.sub.2 and R.sub.3 are the same or different and selected from the group consisting of hydrogen, C.sub.1 -C.sub.12 branched, unbranched or cyclic alkyl, aryl and aralkyl; or R.sub.2 and R.sub.3 taken together form a group of the formula ##STR2## can be used as an inhibitor of the lipoxygenase pathway of the arachidonic acid cascade in animals.
REFERENCES:
patent: 3671558 (1972-06-01), Siddall
patent: 3737450 (1973-06-01), Henrick
patent: 4001428 (1977-01-01), Kosower
Nicolaou Kyriacos C.
Petasis Nicos A.
Seitz Steven P.
Research Corporation
Shippen Michael L.
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