Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1982-11-15
1984-08-28
Rosen, Sam
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
424 88, A61K 3514
Patent
active
044683790
ABSTRACT:
A group of substances derived from human leukocytes (white blood cells) are described that amplify, suppress, or otherwise modulate the response of the immune system to reintroduction of antigens. The described materials are generically effective as to antigens rather than specific as to particular antigens, but the described modulators of immune response are effective only in respect of antigens with which the recipient has previously been challenged. The described materials are extracted from leukocyte dialysates by processes involving high pressure liquid chromatography with specified resin/solvent systems. Uses and pharmaceutical compositions for use of the materials are also described.
REFERENCES:
Wotila-Transfer Factor & Other Immunological Activities of Human Leucocyte Dialysate and Other Dialysates of Mammalian Tissues (1979), pp. 2-4, 6-7, 12-17, 22-23 and 25-27.
Endeavor Corp.
Rosen Sam
Stern Richard H.
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