Leukemia-associated virus immunogen, vaccine and assay

Details Leukemia-associated virus immunogen, vaccine and assay Leukemia-associated virus immunogen, vaccine and assay

1985-12-10

1988-12-27

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

25 or more amino acid residues in defined sequence

530325, 530326, 530327, C07K 706, C07K 708, C07K 710

Patent

active

047941685

ABSTRACT:
The present invention relates to a leukemia-associated virus immunogens, vaccines, antibody combining sites and assays. The immunogens are relatively short polypeptides with peptide sequences corresponding to the antigenic determinant domains of a leukemia-associated virus envelope protein. The immunogens when introduced into a host stimulate the production of antibodies which immunoreact with the polypeptides and the leukemia-associated virus.

REFERENCES:
Elder et al., J. Virol., 46:871-880 (1983).
Cianciolo et al., Nature, 311:515 (Oct. 1984).
Bayer et al., EMBO J., 3:1925-1930 (1984).
Seiki et al., Proc. Natl. Acad. Sci. U.S.A., 80:3618-3622 (1983).
Bosselman et al., J. Virol., 44:19-31 (1982).
Chemical Abstracts, 104:207681j, (1986) (p. 801).

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