Leukaemia inhibitory factor from livestock species and use there

Details Leukaemia inhibitory factor from livestock species and use there Leukaemia inhibitory factor from livestock species and use there

1994-12-01

1997-06-24

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

435375, 435377, 435378, 424 937, 600 33, 800 2, C12N 500, A61K 4900, A61D 700

Patent

active

056416768

ABSTRACT:
Disclosed is the in vitro development of mammalian embryos to the implantation stage by culturing the embryos in a medium containing leukemia inhibitory factor (LIF).

REFERENCES:
patent: 5418159 (1995-05-01), Gough et al.
Gearing et al. (1987) "Molecular Cloning and Expression of cDNA Encoding a Murine Myeloid Luekaemia Inhibitory Factor (LIF)" EMBO J. 6, 3995-4002.
Smith et al. (1988) "Inhibition of Pluripotential Embryonic Stem Cell Differentiation by Purified Polypeptides" Nature 336, 688-690.
Williams et al. (1988) "Myeloid Leukaemia Inhibitory Factor Maintains the Developmental Potential of Embryonic Stem Cells" Nature 366, 684-687.
Robertson et al. (1990) "In Vitro Models of the Maternal-Fetal Interface" in Molecular and Cellular Immunology of the Maternal-Fetal Interface, Wegmenn, et al., eds., Oxford University Press, New york, 191-206.
Gearing et al (1987) EMBO J. 6, 3995-4002.

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