Leucylalany-arginine derivative

Details Leucylalany-arginine derivative Leucylalany-arginine derivative

1981-09-09

1983-11-29

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C10352

Patent

active

044180128

ABSTRACT:
A leucylalanyarginine derivative represented by the formula, ##STR1## wherein R.sub.1 represents hydrogen or an amino-protecting group; R.sub.2 and R.sub.3 represent hydrogen or guanidino-protecting groups; and R.sub.4 represents naphthyl. The above compound is useful as an excellent substrate for various enzymes, such as trypsin, plasmin, kallikrein, urokinase, Cl-esterase and the like. Accordingly, the activity of enzymes can be measured by use of said compound as a substrate.

REFERENCES:
patent: 3886136 (1975-05-01), Claeson et al.
patent: 4137225 (1979-01-01), Af Ekenstam et al.
patent: 4252715 (1981-02-01), Aurell et al.
patent: 4257940 (1981-03-01), Fujii et al.
patent: 4308201 (1981-12-01), Fujii et al.
patent: 4308202 (1981-12-01), Fujii et al.

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