Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2008-01-22
2008-01-22
Bunner, Bridget E. (Department: 1647)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S004000, C436S501000, C530S350000, C530S387100
Reexamination Certificate
active
07320868
ABSTRACT:
The present invention provides compositions and methods relating to avian leptin receptor binding domains. The present invention demonstrates that these compositions are useful for detecting the presence of leptin in a sample and distinguishing free leptin from bound leptin in multiple species. Methods and kits are presented for determining free leptin in a sample from an individual by assaying a sample for the binding of leptin to an avian leptin receptor binding domain, and detecting the bound leptin by using a labeled anti-leptin antibody.
REFERENCES:
patent: 6277592 (2001-08-01), Bidwell et al.
patent: 6297027 (2001-10-01), Spurlock
patent: 6492178 (2002-12-01), Pandian
patent: 2002/0110857 (2002-08-01), Spurlock
patent: 2002/0127642 (2002-09-01), Spurlock et al.
patent: 2002/0137100 (2002-09-01), Illmensee et al.
patent: 2004/0038305 (2004-02-01), Poston et al.
patent: WO 01/30963 (1999-10-01), None
patent: WO 2005/049655 (2003-11-01), None
Horev et al., Molecular cloning and properties of the chicken leptin-receptor (CLEPR) gene, 2000, Molecular and Cellular Endocrinology, vol. 162, p. 95-106.
Kratzsch et al., A rapid, quantitative immunofunctional assay for measuring human leptin, 2002, Hormone Research, vol. 57, pp. 127-132.
Sandowski et al., J. Biological Chemistry, Nov. 29, 2002, pp. 46304-46309, vol. 277 (48), USA.
Haniu et al., J. Biological Chemistry, Oct. 30, 1998, pp. 28691-28699, vol. 273 (44), USA.
Fong et al., Molecular Pharmacology, 1998, pp. 234-240, vol. 53, USA.
Gavrilova et al., J. Biological Chemistry, Nov. 28, 1997, pp. 30546-30551, vol. 272 (48), USA.
Liu et al., Endocrinology, 1997, pp. 3548-3554, vol. 138 (8), USA.
Devos et al., J. Biological Chemistry, Jul. 18, 1997, pp. 18304-18310, vol. 272 (29), USA.
Kratzsch et al., Hormone Research, 2002, pp. 127-132, vol. 57, USA.
Dridi et al., Am. J. Physio. Endocrinol. Metab., 2000, pp. E116-E123, vol. 279, USA.
Wu et al., J. Clinical Endocrinol. Metab., 2002, pp. 2931-2939, vol. 87 (6), USA.
Baumgartner et al., J. Biological Chemistry, Nov. 18, 1994, pp. 29094-29101, vol. 269 (46), USA.
Sinha et al., J. Clinical Investigation, Sep. 1996, pp. 1277-1282, vol. 98 (6), USA.
Maamra et al., Endocrinology, 2001, pp. 4389-4393, vol. 142 (10), USA.
Raver et al., Experimental Biology 2003 Meeting Abstract, Apr. 2003, Abstract No. 571.1, USA.
Ohkubo et al., Biochimica et Biophysica Acta, 2000, pp. 303-308, vol. 1491, USA.
Horev et al., Molecular and Cellular Endocrinology, 2000, pp. 95-106, vol. 162, USA.
Tartaglia et al., Cell, Dec. 29, 1995, pp. 1263-1272, vol. 83, USA.
Takaya et al., Biochemical and Biophysical Research Communications, 1996, pp. 75-83, vol. 225, USA.
Henson et al., Biology of Reproduction, 2000, pp. 1219-1228, vol. 63, USA.
Tartaglia, J. Biological Chemistry, Mar. 7, 1997, pp. 6093-6096, vol. 272 (10), USA.
Janeckova, Physiol. Res., 2001, pp. 4430459, vol. 50, USA.
Bradley et al., Recent Prog. Horm. Res., 2001, pp. 329-358, vol. 56, USA.
Huang et al., Cell Research, 2000, pp. 81-92, vol. 10, USA.
Houseknecht et al., Diabetes, 1996, pp. 1638-1643, vol. 45 (11), USA.
Luoh et al., J. Molecular Endocrinology, 1997, pp. 77-85, Abstract, vol. 18 (1), USA.
Taouis et al., Gene, Feb. 22, 1998, pp. 239-242, vol. 208 (2), USA.
Rock et al., Horm. Metab. Res., Dec. 1996, pp. 748-750, vol. 28 (12), USA.
Gertler et al., FEBS Lett., Jan. 30, 1996, pp. 137-140, vol. 422 (2), USA.
Raver et al., Gen. Comp. Endocrinol., Mar. 2002, pp. 52-58, Abstract, vol. 126 (1), USA.
Taouis et al., Domest. Anim. Endocrinol., Nov. 2001, pp. 319-327, Abstract, vol. 21 (4), USA.
Raver et al., Protein Expr. Purif., Jun. 2000, pp. 30-40, Abstract, vol. 19 (1), USA.
Raver et al., Protein Expr. Purif., Dec. 1998, pp. 403-408, Abstract, vol. 14 (3), USA.
Richards et al., Comp. Biochem. Physiol. B. Biochem. Mol. Biol., Dec. 2003, pp. 833-847, Abstract, vol. 136 (4), USA.
Gonzalez et al., Endocrine, Jul. 2003, pp. 185-195, vol. 21 (2), USA.
Yiannakouris et al., J. Clin. Endocrinol. & Metab., 2001, pp. 4434-4439, vol. 86 (9), USA.
Kiess et al., J. Clin. Endocrinol. & Metab., 2001, pp. 4472-4479, vol. 86 (9), USA.
Gertler Arieh
Krishna Radha
Bunner Bridget E.
Dang Ian
Soehnge Holly O.
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