Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2011-06-28
2011-06-28
Lucas, Zachariah (Department: 1648)
Chemistry: molecular biology and microbiology
Vector, per se
C435S005000, C424S199100, C424S204100, C424S207100
Reexamination Certificate
active
07968332
ABSTRACT:
The invention relates to an immunogenic composition comprising a recombinant vector characterized in that it comprises a polynucleotide comprising the cis-acting central initiation region (cPPT) and the cis-acting termination region (CTS), these regions being of retroviral or retroviral-like origin, said vector comprising in addition a defined nucleotide sequence (transgene or sequence of interest) and regulatory signals of retrotranscription, expression and encapsidation of retroviral or retroviral-like origin, wherein the composition is capable of inducing or of stimulating a cell-mediated response for instance a CTL (Cytotoxic T Lymphocytes) response or a CD4 response, against one or several epitopes encoded by the transgene sequence present in the vector.
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Charneau Pierre
Firat Hüseyin
Zennou Veronique
Centre National de la Recherche Scientifique
Humphrey Louise
Institut Pasteur
Law Office of Salvatore Arrigo and Scott Lee, LLP
Lucas Zachariah
LandOfFree
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