Lens useful in inhibiting the production of melatonin and lens p

Optics: eye examining – vision testing and correcting – Spectacles and eyeglasses – With antiglare or shading

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351 44, 351165, G02C 900

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active

052744035

ABSTRACT:
A lens that transmits light expressing a transmission curve which has a low cut-in wavelength in the vicinity of 400 nm, rising gradually in terms of percentage of light transmitted, to a maximum in the vicinity of 509 nm and then descending in equal manner, in terms of wavelength and percentage of light transmitted, to a high wavelength cut-off in the vicinity of 600 nm, and method of manufacture. The overall transmission curve expresses essentially a Gaussian configuration. The transmission curve is congruent with the rod mediated portion of the electromagnetic wavelength spectrum for the human eye, also described as scotopic in character and believed to be operative in maximizing the inhibition of melatonin secretion, a substance produced by the human pineal gland.

REFERENCES:
Brainard et al. "Effect of light Irradiance and Wavelength on the Syrain Hamster Reproductive System", Endocrinology,-1986.
Lewy et al. "Light Supresses Melatonin Secretion in Humans", Science vol. 210 Dec. 1980.
Lewy et al. "Melatonin, Light & Chronobiological Disorders", CIBA Foundation Symp., vol. 117 pp. 23-252,-1985.
Lewry et al. "SuperSensitivity to Light:Possible Tract Marker for Manic Depressive Illness", Am. J. Psychiatry Jun. 1985.
Doan et al. Scheduled Exposive to Daylight:A Potential Strategy to Reduce "Set Lag" following Transmeridian Flight, Psych pharmacology Blt. vol. 20 No. 3, 1984.
Lissoni et al., "A Clinical Study of the Pineal Gland Activity in Oncologic Patients", Cancer, Feb. 15, 1986.
Fevre-Montange et al., "Effects of Jetlag on Hormonal Patterns Journal of Clinical Endocrinology & Metabolism", vol. 52, No. 4, 1981.
Cardinali et al. "Pineal gland, photoperiodic responses and puberty", J. of Endocrinol. Invest 7:157,-1984.

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