Length polymorphisms in (dC-dA).sub.n.(dG-dT).sub.n sequences an

Details Length polymorphisms in (dC-dA).sub.n.(dG-dT).sub.n sequences an Length polymorphisms in (dC-dA).sub.n.(dG-dT).sub.n sequences an

1994-04-04

1996-12-10

Leguyader, John L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 231, 536 243, 536 2431, C12Q 168, C12P 1934, C07H 2104

Patent

active

055829791

ABSTRACT:
Abundant interspersed repetitive DNA sequences of the form (dC-dA).sub.n.(dG-dT).sub.n have been shown to exhibit length polymorphisms. The polymorphisms can be used to identify individuals as in paternity and forensic testing, and can be used to map genes which are involved in genetic diseases or in other economically important traits. The polynucleotide provided consists of a DNA fragment, preferably .ltoreq.300 base pairs in length containing one or more blocks of tandem dinucleotide repeats (dC-dA).sub.n.(dG-dT).sub.n wherein n.gtoreq.6 and preferably .gtoreq.10.

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