Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1991-02-15
1993-03-16
Wax, Robert A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
530413, 530416, 530855, C07K 1300, C07K 302, C07K 328
Patent
active
051945894
ABSTRACT:
The present invention comprises a biochemically pure protein, termed antistasin, which exhibits both antimetastatic and anticoagulant properties. Methods of producing the protein and methods of using the protein to inhibit or reduce metastasis and/or coagulation of blood are disclosed. The complete amino acid sequences of antistasin and some variants have been determined from purified protein and cloned cDNAs.
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Ekstrom Richard C.
Pennsylvania Hospital
Wax Robert A.
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