Lectin-containing anti-viral vaccines for domestic animals and m

Details Lectin-containing anti-viral vaccines for domestic animals and m Lectin-containing anti-viral vaccines for domestic animals and m

1982-10-05

1984-09-11

Marantz, Sidney

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3912

Patent

active

044709676

ABSTRACT:
Anti-viral vaccines for domestic animals are prepared from glycoprotein envelope whole virus or antigenic glycoprotein obtained therefrom by complexing the glycoprotein antigenic agent with a lectin, which is preferably a mitogenic lectin. The recovery of the immunizing agent from an aqueous solution or suspension is facilitated since the lectin-glycoprotein complex is readily recoverable. The mitogenic lectin administered in the vaccine with the glycoprotein antigen can enhance the anamnestic response, in effect, acting as an adjuvant.

REFERENCES:
patent: 3994870 (1976-11-01), Neurath et al.
patent: 4203893 (1980-05-01), Pery et al.
patent: 4291019 (1981-09-01), Lupton et al.
patent: 4335105 (1982-06-01), Gough
patent: 4371515 (1983-02-01), Chu
Velicer et al., Journal of Virology, 1978, 27, 1, pp. 205-217.
Brown and Hunt, "Lectins", in International Review of Cytology, vol. 52, pp. 277-278, 292-297 (Academic Press, 1978).

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