Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-08-28
2000-08-29
Krass, Frederick
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514922, 514925, 514926, 514927, A61K 3816
Patent
active
06110891&
ABSTRACT:
This invention provides methods for: the control of mucosal cell proliferation; the reduction and/or treatment of damage caused by a cell-damaging agent; and for the reduction and/or treatment of a metabolic disorder.
The methods comprise administering to an individual in need of control or reduction and/or treatment on effective amount of a lectin.
The invention takes advantageous of the protective and repair capabilities of lectins. It is particularly useful in the prevention and treatment of animals undergoing radiotherapy and/or chemotherapy for cancer.
REFERENCES:
patent: 4742046 (1988-05-01), Bliah
patent: 5102870 (1992-04-01), Florine et al.
patent: 5840771 (1998-11-01), Oldham et al.
Josiane Wantyghem et al., "Purification and Characterization of Robinia Pseudoacacia Seed Lectins", The Biochemical Journal, vol. 237, No. 2, Jul. 15, 1986, pp. 483-489.
Bardocz Zsuzsanna Magdolna
Fish Neil William
Koteles Gyorgy J.
Palmer Richard Michael John
Pusztai Arpad Janos
Alizyme Therapeutics Ltd.
Corless Peter F.
Krass Frederick
O'Day Christine C.
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