LC/FTIR System with thermospray solvent separation

Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Sample mechanical transport means in or for automated...

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73 611C, 250338, 356 36, 356346, 422 70, 422 91, 436 44, 436161, G01J 100, G01N 2113, G01N 3002

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045527237

ABSTRACT:
Effluent from an LC is passed through a thermospray nozzle which flash vaporizes substantially all of the solvent while directing any sample components as a collimated beam onto a moving tape so that the various components form spots on the tape. The tape is moved along a path that intercepts the optical path of an FTIR spectrometer whereby IR energy from the spectrometer is passed through each sample component and is then spectrally analyzed. The tape can be wound up, stored, and later used for further analysis of the spots, as desired, in the FTIR spectrometer.

REFERENCES:
patent: 3667917 (1972-06-01), Brandt
patent: 3904364 (1975-09-01), Dodson
patent: 4055987 (1977-11-01), McFadden
patent: 4056969 (1977-11-01), Barringer
patent: 4420566 (1983-12-01), Jessop et al.
Blakely et al., Analytical Chemistry, vol. 52, No. 11, Sep. 1980, pp. 1636-1641.
Amino Acid Analysis, J. M. Rattenbury, 1981, pp. 16-18.
"The Estimation of the Leucine Isomersion Protein Hydrolysates by Infrared Analysis" by S. E. Darmon et al., Biochemical Journal, vol. 42, 1948, pp. 508-516.

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