Laxative compositions

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Capsules

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Details

424455, 424457, 424463, 424464, 424474, 424480, 424482, 4241951, 514892, A61K 120, A61K 922, A61K 952

Patent

active

053975731

ABSTRACT:
Laxative compositions containing sennoside and menthol, pharmaceutically-acceptable esters of menthol, or mixtures thereof, preferably as peppermint oil; and methods for treating constipation by orally concurrently administering to the lower gastrointestinal tract of a person in need of such treatment sennoside and menthol.

REFERENCES:
patent: 4256875 (1981-03-01), Gabriel et al.
patent: 4402944 (1983-09-01), Callahan et al.
patent: 4476121 (1984-10-01), Moss
patent: 4511561 (1985-04-01), Madaus et al.
patent: 4595592 (1986-06-01), Hietala
patent: 4766004 (1988-08-01), Moskowitz
patent: 4842865 (1989-06-01), Durr et al.
patent: 4857331 (1989-08-01), Shaw et al.
patent: 5173296 (1992-12-01), Andre et al.
patent: 5232699 (1993-08-01), Colliopoulos
patent: 5258181 (1993-11-01), Cregier et al.
Perdiem.RTM. (sold by Rorer Consumer Pharmaceuticals), Physicians' Desk Reference for Nonprescription Drugs, 10th Edition (Medical Economics Company Inc.; 1989) pp. 666-667.
Ex-Lax.RTM. Choclated Laxative (sold by Sandoz Consumer), Physicians' Desk Reference for Nonprescription Drugs, 10th Edition (Medical Economics Company Inc.; 1989), p. 677.
The Merck Index, 10th Edition (1983), No. 5662 ("Menthol"), No. 5663 (I-Menthone) and No. 5664 (Menthyl Acetate).
The Merck Index, 10th Edition (1983), No. 8298 (Senna) and No. 8299 (Sennoside A&B) "Proceedings, First International Symposium on Senna", Pharmacology, 36, Suppl. 1 (Karger; 1988).
The Lawrence Review of Natural Products, Topic "Peppermint" (copyright 1990 by Facts and Comparisons.
British Pharmacopoeia, "Peppermint Oil", pp. 422-423 (1988).
National Formulary XVII, "Peppermint Oil", pp. 1956-1957 (1990).

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