Lawsonia intracellularis vaccine

Details Lawsonia intracellularis vaccine Lawsonia intracellularis vaccine

2005-07-13

2009-02-17

Mondesi, Robert B (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C435S069100, C435S069700, C536S023700, C424S190100

Reexamination Certificate

active

07491401

ABSTRACT:
The present invention relates i.a. to nucleic acid sequences encoding novelLawsonia intracellularisproteins. It furthermore relates to DNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Also it relates to host cells comprising such nucleic acid sequences, DNA fragments, recombinant DNA molecules and live recombinant carriers. Moreover, the invention relates to proteins encoded by these nucleotide sequences. The invention also relates to vaccines for combatingLawsonia intracellularisinfections and methods for the preparation thereof. Finally the invention relates to diagnostic tests for the detection ofLawsonia intracellularisDNA, the detection ofLawsonia intracellularisantigens and of antibodies againstLawsonia intracellularis.

REFERENCES:
patent: 5610059 (1997-03-01), Joens et al.
patent: 5714375 (1998-02-01), Knittel et al.
patent: 5885823 (1999-03-01), Knittel et al.
patent: 6605696 (2003-08-01), Rosey
patent: 6921536 (2005-07-01), Jacobs et al.
patent: 2001169787 (2001-06-01), None
patent: WO 9304163 (1993-03-01), None
patent: WO 9639629 (1996-12-01), None
patent: WO 97 20050 (1997-06-01), None
patent: WO 00 69905 (2000-11-01), None
patent: WO 0069903 (2000-11-01), None
patent: WO 0069904 (2000-11-01), None
patent: WO 0069906 (2000-11-01), None
Bowie et al (Science, 1990, 257:1306-1310.
Herbert et al (The Dictionary of Immunology, Academic Press, 3rd Edition, London, 1985, pp. 58-59.
Roitt et al (Immunology, 1993, Mosby, St. Lois, p. 7.7-7.8.
Holmes (Exp. Opin.Invest. Drugs, 2001, 10(3):511-519).
Abaza et al. (Journal of Protein Chemistry, vol. 11, No. 5, 1992, pp. 433-444.
Coleman et al. (Research in Immunology, 1994; 145(1): 33-36).
McOrist et al , Int J Syst Bacteriol. Oct. 1995;45(4):820-5.
Database Swall ′Online!, Oct. 1, 2000, retrieved from EBI Database accession No. Q9KQE0.
Database Swall ′Online!, May 1, 1999, retrieved from EBI Database accession No. Q9ZCH2.
Kim J et al: “Immunohistochemistry and Polymerase Chain Reaction for the Detection . . . ” J. of Veterinary Med. Science.; V7, N 62, Jul. 2000, p. 771-773.
Dale C Jane H et a: “Identification and sequencing of the groE operon and flanking . . . ”, Microbiology, Society for General . . GB, vol. 144, No. 8, Aug. 1998, pp. 2073-2084.
McOrist, S., et al: “Reproduction of Porcine Proliferative Enteropath . . . ” Infection and Immunity. vol. 61, (1993) No. 10, 4286-4292.
McOrist, S., et al: “Immunocytological Responses in Porcine Proliferative Enteropathies” Infection and Immunity. vol. 60, (1992) No. 10, 4184-4191.
McOrist, S., et al: “Antigenic Analysis of Campylobacter Species and an Intracellular Campylobacter-like Organism . . . ” Invection and Immunity vol. 57, N3,p. 957-962.
Herrick, J.B.: “Large Anim. Pract.” vol. 19, (1998) No. 6, 15.
Lawson, G.H. et al: “Vet. Rec.” vol. 107, (1980) No. 18, 424-425.
Holyoake, P.K., et al: “J. Clin. Microbiol.” vol. 32, (1994) No. 8, 1980-1985.
Burgess, W. H. et al.: “Possible Dissociation of the Heparin-binding and Mitogenic Activities . . . ” The J. of Cell Biology (1990) V111 p. 2129-2138.
Ellis, R.W. “New Technologies for Making Vaccines” VaccinesPlotkin, 5.A. et al. (eds) (1988) published by W.B. Saunders Co. (Philadelphia) p. 568-575.
Jobling, M.G. et al “Analysis of structure and function of the B subunit of cholera toxin . . . ” Molecular Microbiology (1991) V5, N7, p. 1755-1767.
Lazar, E. et al. “Transforming Growth Factor a: Mutation of Aspartic Acid 47 and Leucine 48 Results . . . ” Molecular and Cellular Biology (1988) V8, N3, p. 1247-1252.
McCluskey, J. et al. “LsaA, an Antigen Involved in Cell Attachment and Invasion, Is Expressed . . . ” Infection and Immunity (2002) V70, N6, p. 2899-2907.
Rudinger, J.A. “Characteristics of the amino acids as components of a peptide hormone sequence” Peptide Hormones (1976) edited by J.A. Parsons, University Park.Press, p. 6.
Smith, et al. “Gamma Interferon Influences Intestinal Epithelial Hyperplasia caused byLawsonia. . . ” Infection and Immunity (2000) V68, N12, p. 6737-6743.

Affiliated with

Also associated with

Rating

Lawsonia intracellularis vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lawsonia intracellularis vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lawsonia intracellularis vaccine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4066726