Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2007-12-25
2007-12-25
Graser, Jennifer (Department: 1645)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S243000, C435S366000, C435S383000, C435S395000, C435S403000, C424S093400, C424S234100, C424S825000
Reexamination Certificate
active
10891745
ABSTRACT:
The present invention relates toLawsonia intracellularisvaccines and methods for protecting against and diagnosingL. intracellularisinfection. The products and processes of the invention are attainable, in part, as the result of an improved method for cultivating large scale supplies ofL. intracellularis, including both a novel isolate ofL. intracellularisof European origin and a method of preparing a lyophilized product containing the attenuated European isolate as vaccine product.
REFERENCES:
patent: 5714375 (1998-02-01), Knittel et al.
patent: 5885823 (1999-03-01), Knittel et al.
NIH Guide, vol. 22, No. 28, Multicomponent Vaccine Development, Aug. 6, 1993.
Fattom et al. Vaccine vol. 17, No. 2, Jan. 1999, pp. 126-133.
Abstract of the General Meetings No. 101 May 23, 2001: Session No. 263/Z Abstract Z-40; Efficacy of an AvirulentLawsonia intracellularisVaccine in Swine; J.J. Kroll et al.
International Search Report Reference No. PCT/US2004/022704.
P.K. Holyoake et al; Enzyme-Linked Immunosorbent Assay for Measuring Ileal Symbiont Intracellularis-Specific Immunoglobulin G Response in Sera of Pigs;Journal of Clinical Microbiology Aug. 1994 vol. 32 No. 8 pp. 1980-1985; American Society for Microbiology.
Knittel Jeffrey P.
Kroll Jeremy J.
Roof Michael B.
Boehringer Ingelheim Vetmedica, Inc.
Devlin Mary-Ellen M.
Graser Jennifer
Morris Michael P.
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