Lawsonia intracellularis cultivation, anti-Lawsonia intracellula

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of...

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435245, 4352521, 435366, 435383, 435395, 435403, 424 934, 4242341, 424825, C12N 120, C12N 100, A61K 3902

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active

058858237

ABSTRACT:
A method for large scale cultivation and attenuation of L. intracellularis bacteria by inoculating cells with L. intracellularis bacteria to infect the cells, incubating the infected cells in a reduced oxygen concentration and maintaining the infected cells in suspension. Anti-L. intracellularis vaccines are prepared from cultures grown in suspension. Diagnostic agents are also disclosed.

REFERENCES:
patent: 4132597 (1979-01-01), Kvanta
patent: 4237218 (1980-12-01), Monthony et al.
patent: 4880739 (1989-11-01), Yamada et al.
patent: 4904597 (1990-02-01), Inoue et al.
patent: 4920048 (1990-04-01), Diderichsen
patent: 5126265 (1992-06-01), Cidaria et al.
patent: 5230912 (1993-07-01), Yajima et al.
patent: 5296221 (1994-03-01), Mitsuoka et al.
patent: 5318908 (1994-06-01), Seki et al.
patent: 5338670 (1994-08-01), Sekura et al.
patent: 5380657 (1995-01-01), Schaefer et al.
patent: 5436001 (1995-07-01), Krawer
patent: 5610059 (1997-03-01), Joens et al.
Brock, Thomas D. et al., "Immunization for Infectious Disease", Biology of Microorganisms, Prentice-Hall, Inc., 4th Ed., (19 ), pp. 557-558.
McOrist et al., Porcine Proliferative Enteropathy, The Veterinary Record vol. 132, p. 368, 1993.
Lawson et al., Attempts to Cultivate the Campylobacter-like Organism of the Proliferative Enteropathies, Assoc. of Vet. Teachers and Research Workers, Abstract, Apr. 8-11, 1990.
S. Jasni et al., "Reproduction of Proliferative Enteritis in Hamsters With a Pure Culture of Porcine Ileal Symbiont Intracellularis", Veterinary Microbiology 41, pp. 1-9 (1994).
S. McOrist et al., "Synergism of Ileal Symbiont Intracellularis and Gut Bacteria in The Reproduction of Porcine Proliferative Enteropathy", Veterinary Record, 134, pp. 331-332 (1994).
S. McOrist et al., "Antimicrobial Susceptibility of Ileal Symbiont Intracellularis Isolated From Pigs With Proliferative Enteropathy", Journal of Clinical Microbiology, 33, pp. 1314-1317 (1995).
S. McOrist et al., "Entry of the Bacterium Ileal Symbiont Interacellularis Into Cultured Enterocytes and its Subsequent Release", Research in Veterinary Science, 59, pp. 255-260 (1995).
S. McOrist, et al., In Vitro Testing Of Antimicrobial Agents For Proliferative Enteropathy (Ileitis), Swine Health and Production, pp. 146-149 (Jul. and Aug. 1995).
S. McOrist et al., "Characterization of Lawsonia intracellularis gen. nov., sp. nov., the Obligately Intracellular Bacterium of Porcine Proliferative Enteropathy", International Journal of Systematic Bacteriology, 45, pp. 820-825 (1995).
G.H.K. Lawson et al., "Infection of Cultured Rat Enterocytes by Ileal Symbiont Intracellularis Depends on Host Cell Function and Actin Polymerisation", Veterinary Microbiology, 45, pp. 339-350 (1995).
S. McOrist et al., Vet. Pathol., vol. 26, 260-67 (1989).
S. McOrist et al., Vet. Pathol., vol. 26, 260-64 (1989).
C. Gebhart et al., Int'l J. of Systemic Bacteriology, vol. 43, No. 3, 533-38 (1993).
S. McOrist et al., Infection and Immunity, vol. 61, No. 10, 4286-92 (1993).
G. Lawson et al., J. of Clinical Microbiology, vol. 31, No. 5, 1136-42 (1993).
H. Stills, Infection and Immunity, vol. 59, No. 9, 3227-36 (1991).
S. McOrist et al., Int'l. J. of Systemic Bacteriology, vol. 45, No. 4, 820-25 (1995).
S. McOrist et al., Vet. Rec. 121:421-422 (1987).
Jones et al., J. Clin. Microbiol., 31:2611-2615 (1993).
McOrist et al., Vet. Microbiaol. 41 (1994) 205-212.
Gary F. Jones as reported in his Ph.D. thesis, University of Minnesota, Minneapolis, MN (Jun. 1993).
Peace et al., Comparative Analysis of the 16S rRNA Gene Sequence of the Putative Agent of Proliferative Ileitis of Hamsters, Int'l. J. of Syst. Bacter. vol. 44, pp. 832-835, 1994.
Tseneva et al., Invasiveness and Cytotoxicity as Criteria Used for the Evaluation of the Attenuation of Yersinia, Zh Mikrobiol. Epidemiol. Immunobiol. 1988 (Biosis Abstract No. 89:224753).

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