Latex polymer particles containing fluorescent substance or...

Details Latex polymer particles containing fluorescent substance or... Latex polymer particles containing fluorescent substance or...

2003-12-19

2008-12-30

Choi, Ling-Siu (Department: 1796)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

C526S325000, C526S319000, C526S307500

Reexamination Certificate

active

07470763

ABSTRACT:
This invention provides a method to effectively incorporate inorganic fluorescent substance or inorganic contrast medium into latex polymer particles which are used for diagnostic test or the like, and also provides thus produced fluorescent substance-containing latex polymer particles which show decreased non-specific adsorption of protein or the like. Said latex polymer particles are produced by making latex-forming monomer, macromer which has at least a hydrophilic polymer segment and an inorganic fluorescent substance or an inorganic contrast medium co-existent simultaneously in an aqueous medium, and subjecting them to a polymerization reaction.

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Matsuya et al., Anal. Chem., 75, 6124-6132 (2003).
Matsuya et al., “A Core—Shell-Type Fluorescent Nanosphere Possessing Reactive Poly(ethylene glycol) Tethered Chains on the Surface for Zeptomole Detection of Protein in Time-Resolved Fluorometric Immunoassay”, Anal. Chem. 2003, 75, 6124-6132.

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