Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2006-09-12
2006-09-12
Swartz, Rodney P (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S009100, C424S009200, C424S130100, C424S139100, C424S150100, C424S184100, C424S185100, C424S234100, C435S004000, C435S325000, C435S366000, C435S372000
Reexamination Certificate
active
07105170
ABSTRACT:
Provided herein is an in vitro granuloma model and methods of its use. Methods of detecting and/or diagnosing latent tuberculosis in a subject are also provided, as are latency-specific antigens (and antibodies thereto), such as α-crystallin, and methods of identifying and using such molecules. Also provided are immunostimulatory compositions, for instance for use in eliciting an immune response in a subject, such as an immune response to a latent tuberculosis infection. Kits for carrying out the provided methods are also described.
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Beall David S.
Birkness Kristin A.
Deslauriers Manon
King Peter
Quinn Frederick D.
Klarquist & Sparkman, LLP
Swartz Rodney P
The United States of America as represented by the Department of
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