Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-12-11
2007-12-11
Spector, Lorraine (Department: 1647)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S351000, C514S002600
Reexamination Certificate
active
11523702
ABSTRACT:
The present invention provides a method for providing latency to a pharmaceutically active agent. The method has application in overcoming the toxic effect of systemic administration of potent biological agents. The method comprises associating a fusion protein comprising a latency associated peptide and a proteolytic cleavage site with a pharmaceutically active agent. The fusion protein also has application in providing site specific activation to a latent pharmaceutically active agent.
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Adams Gillian
Chernajovsky Yuti
Dreja Hanna Stina
Queen Mary and Westfield College
Shafer Shulamith H.
Spector Lorraine
Sterne Kessler Goldstein and Fox P.L.L.C.
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