Optics: measuring and testing – By dispersed light spectroscopy – With raman type light scattering
Reexamination Certificate
2005-05-24
2005-05-24
Evans, F. L. (Department: 2877)
Optics: measuring and testing
By dispersed light spectroscopy
With raman type light scattering
Reexamination Certificate
active
06897950
ABSTRACT:
Methods and systems for studying microscopic particles are provided. An optical trap for a selected microscopic particle can be formed with a laser beam at a first power level. The laser beam can have a variable power level associated therewith. The variable power level can be increased to a second power level. The laser beam at the second power level can produce Raman scattering signals. The second power level can provide sufficient excitation energy to the selected microscopic particle to produce Raman scattering signals and the second power level is higher than the first power level. A Raman spectrum can be detected from the Raman scattering signals produced by the laser beam at the second power level.
REFERENCES:
patent: 6055106 (2000-04-01), Grier et al.
patent: 6067859 (2000-05-01), Kas et al.
patent: 6100975 (2000-08-01), Smith et al.
patent: 6139831 (2000-10-01), Shivashankar et al.
patent: 6159749 (2000-12-01), Liu
patent: 6373567 (2002-04-01), Wise et al.
patent: 2001-14374 (2001-05-01), None
Lankers, M., et al., “Raman and Florescence Spectra of Single Optically Trapped Microdroplets in Emulisions” Applied Spectroscopy vol. 48, No. 9, 1994, pp. 1166-1168.
Ajito, K., “Combined Near-Infrared Raman an Microprobe and Laser Trapping System: Application to the Analysis of a Single Organic Microdroplet in Water”, Applied Spectroscopy, vol. 52, No. 3, 1998, pp. 339-342.
Afzal, Robert, “Optical tweezers using a diode laser”, Rev. Sci., Instrum. 63(4), Apr. 1992, pp. 2157-2163.
Ajito et al.; “Near-infrared Raman spectroscopy of single particles”trends in analytical chemistry20:5 255-262 (1002).
A. Ashkin; “Acceleration and Trapping of Particles by Radiation Pressure”Physical Review Letters24:4 156-159 (1970).
Ashkin et al.; “Observation of a single-beam gradient force optical trap for dielectric particles”Optics Letters11:5 288-290 (1986).
Ashkin et al.; “Optical trapping and manipulation of single cells using infrared laser beams”Nature330:24 769-771 (1987).
Baraga et al.; “Rapid Near-Infrared Raman Spectroscopy of Human Tissue with a Spectrograph and CCD Detector”Applied Spectroscopy46:2 187-190 (1992).
Bell et al.; “Analysis of luminescent samples using subtracted shifted Raman spectroscopy”Analyst 1231729-1734 (1998).
Brennan III et al.; “Near-Infrared Raman Spectrometer Sytems for Human Tissue Studies”Applied Spectroscopy51:2 201-208 (1997).
Furukawa et al.; “Optical trapping of metallic particles by a fixed Gaussian beam”Optics Letters23:3 216-218 (1998).
Gogotsi et al.; “Cyclic nanoindentation and Raman microspectroscopy study of phase transformation in semiconductors”J. Mater. Res. 15:4 871-879 (2000).
He et al.; “Direct Observation of Transfer of Angular Momentum to Absorptive Particles from a Laser Beam with a Phase Singularity”Physical Review Letters75:5 826-829 (1995).
Hoffman et al.; “Substitutional carbon in germanium”Physical Review B55:17 167-173 (1997).
Li et al.; “Coherent transient amplification in inhomogenously broadened ribidium atoms by diode-laser frequency switching”Optics Letters21:13 982-984 (1996).
Li et al.; “Surface enhanced resonance Raman spectroscopy of rhodamine 6G adsorbed on silver electrode in lithium batteries”Chemical Physics Letters330 249-254 (2000).
Mosier-Boss et al.; “Fluorescence Rejection in Raman Spectroscopy by Shifted-Spectra, Edge Detection, and FFT Filtering Techniques”Applied Spectroscopy49:5 630-638 (1995).
Neddersen et al.; “Laser Ablation of Metals: A New Method for Preparing SERS Active Colloids”Applied Spectroscopy47:12 1959-1964 (1993).
Neuman et al.; “Characterization of Photodamage toEscherichia coliin Optical Traps”Biophysical Journal77 2856-2863 (1999).
Nie et al.; “Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering”Science275 1102-1106 (1997).
O'Neil et al.; “Three-dimensional optical confinement of micron-sized metal particles and the decoupling of the spin and orbital angular momentum within an optical spanner”Optics Communications185 139-143 (2000).
Roosen et al.; “The TEM01 Mode Laser Beam—A Powerful Tool for Optical Levitation of Various Types of Spheres”Optics Communications26:3 432-436 (1978).
Sasaki et al.; “Optical trapping of a metal particle and a water droplet by a scanning laser bean”Appl. Phys. Lett. 60:7 807-809 (1992).
Sato et al.; “Optical trapping of microscopic metal particles”Optics Letters19:22 1807-1809 (1994).
Schuster et a.; “Single-cell analysis of bacteria by Raman microscopy; spectral information on the chemical composition of cells and on the heterogenity in a culture”Journal of Microbiological Methods42 29-38 (2000).
Shreve et al.: “Effective Rejection of Fluorescence Interference in Raman Spectroscopy Using a Shifted Excitation Difference Technique” Applied Spectroscopy 46:4 707-711 (1992).
Sureau et al.; “An Ultraviolet Micro-Raman Spectrometer: Resonance Raman Spectroscopy within Single Living Cells”Applied Spectroscopy44:6 1047-1051 (1990).
Karel Svoboda; “Biological Applications of Optical Forces”Annu. Rev. Biophys. Biomol. Struct. 23 247-285 (1994).
Wood et al.; “Micro-Raman characterization of the R to T state transition of haemoglobin within a single living erythrocyte”Biochimica et Biophysica Acta1539 58-70 (2001).
Dinno Mumtaz A.
Li Yong-Qing
East Carolina University
Evans F. L.
Geisel Kara
Myers Bigel & Sibley & Sajovec
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