Laser scanning optical system and laser scanning optical apparat

Radiant energy – Luminophor irradiation

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G01N 2164

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active

057961123

ABSTRACT:
A fluorescent microscope includes a laser scanning unit having a stage for supporting a fluorescent sample, a laser beam generator and a beam scanning unit for causing a laser beam from the generator to spot scan a sample to cause fluorescence generated by multi-photon absorption. A first detector detects fluorescence emitted from a side of the sample on which the laser beam is incident to output a first signal corresponding to detected fluorescence. A second detector detects fluorescence emitted from a side of the sample from which the laser beam, having been transmitted through the sample, is emitted from the sample. The second detector produces a second signal corresponding to the detected fluorescence. The first and second signals are summed and amplified. A display is provided for a microscopic image of the sample in synchronization with the scanning of the laser beam, based on the amplified summed signals.

REFERENCES:
patent: 2759393 (1956-08-01), McLeod
patent: 3999855 (1976-12-01), Hirschfeld
patent: 4179708 (1979-12-01), Sheng
patent: 4623776 (1986-11-01), Buchroeder
patent: 4887592 (1989-12-01), Loertscher
patent: 5034613 (1991-07-01), Denk
patent: 5080456 (1992-01-01), Katz
Denk et al., "Two-Photon Laser Scanning Fluorescence Microscopy," Science, vol. 248, Apr. 6, 1990, pp. 73-76.
Tanaka et al., "Generation of Bessel-Beam Spot By An Axicon Prism," pp. 22-29, Proc. 10th Mtg, Japan Society for Laser Microscopy, Japan, Nov. 27, 1992.
Arimoto et al., Imaging Properties of Axicon In A Scanning Optical System, Applied Optics, vol. 31, No. 31, pp. 6653-6657, 1 Nov. 1992, New York, U.S.
Tanaka et al., "Generation of Bessel-Beam Spot By An Axicon Prism," Proceedings 10th Meeting, Japan Society for Laser Microscopy, Tsukuba, Japan, Nov. 27, 1992.
Rioux et al., "Linear, Annular, and Radial Focusing With Axions and Applications to Laser Machining," Applied Optics, 17 (10), May 15, 1978, pp. 1532-1536.

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