Laser manipulation apparatus and cell plate used therefor

Radiant energy – Electrically neutral molecular or atomic beam devices and...

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H05H 304

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active

059526513

ABSTRACT:
A laser manipulation apparatus for trapping and separating an optional micro-sample comprising a cell plate having a first cell for storing a liquid medium containing micro-sample s and a second cell for storing a liquid medium not containing micro-sample s each of the first and second cells being opened at the upper surface, in communication with each other by way of a narrow induction channel for inhibiting free movement of the micro-sample s, an optical trapping system for irradiating and trapping a single micro-sample out of a group of micro-sample s dispersed and suspended in the liquid medium stored in the first cell and a sample separation device for moving the single micro-sample from the first cell through the induction channel into the second cell.

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patent: 5689109 (1997-11-01), Schutze
Sakano et al., "A study on the damages due to the Lasser Irradiation", Department of Electrical and Electronic Engineering, Toyohashi University of Technology, Oct. 1991, pp. 279-282.
Bryant et al., "Absolute Optical Cross Sections of Cells and Chloroplasts", Archives of Biochemistry and Biophysics 135, 1969, pp. 97-108.
Dinkel et al., "Remote two-photon excited fluorescence sensing in a stimulated fermentation broth", Analytica Chimica Acta, 236/1992, pp.131-136.
Ashkin et al., "Optical Trapping and Manipulation of Viruses and Bacteria", Mar. 20, 1987, pp. 1517-1520.
Ashkin et al., "Optical trapping and manipulation of single cells using infrared laser beams", Dec. 1987, Nature vol. 330, pp.769-771.

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