Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1991-12-18
1993-08-17
Kepplinger, Esther L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
422 8205, 422 8209, 435 723, 435 724, 435 732, 436526, 436805, 436806, 436813, 436817, 356337, C12Q 170, G01N 33553
Patent
active
052368246
ABSTRACT:
An in-situ laser magnetic immunoassay ("LMIA") method which eliminates the step of B/F separation generally required in the labeling method of immunoassays. The laser magnetic immunoassay permits a quantitative determination of a target immunological substance, for example, an antigen, an antibody, lymphocytes, viruses, tumorous cells and infections cells, in an analyte solution containing both bound and free species. A transitory increase in the magnetophoretic scattering of laser beam is observed when the analyte solution contains magnetic-labeled, bound target analyte, while no such increase is observed in a control test solution, containing only the relevant reagents. A magnetophoretic LMIA apparatus is provided which includes a magnetic gradient generating device which forms an integral part of the in-situ LMIA.
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Arishima Koichi
Fujiwara Koichi
Hoshino Mitsutoshi
Hoshino Yasushi
Mizutani Hiroko
Kepplinger Esther L.
Nippon Telegraph and Telephone Corporation
Wolski Susan C.
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