Laser immunoassay

Details Laser immunoassay Laser immunoassay

1977-06-13

1979-10-23

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

23230B, 250461B, 331DIG1, 356318, 424 8, 424 12, 422 80, G01N 3316, G01N 2122, H01S 323

Patent

active

041719565

ABSTRACT:
An immune assay for tracing processes and reactions employs a narrow band laser tuned to the absorption line of a tracer isotope coupled chemically to a carrier molecule of protein. The carrier molecule is reacted with another molecule, the reaction products are vaporized, and resonance fluorescence from the tracer isotope illuminated by the laser is measured. Amplitude of the fluorescence signal provides a direct measure of the number of isotope-tagged molecules present after the reaction of interest.

REFERENCES:
patent: 3939350 (1976-02-01), Kronick
patent: 3984533 (1976-10-01), Uzgiris
patent: 4011044 (1977-03-01), Uzgiris
patent: 4020151 (1977-04-01), Bolz
patent: 4036946 (1977-07-01), Kleinerman
patent: 4058732 (1977-11-01), Wieder
Fairbank et al., Jour. of the Optical Society, 65, 199-204 (1975).
Wang, Combustion Science and Tech., 13, 212 (1976).
Hurst et al., Applied Physics Letters, 30, 229-231 (1977).
Chemical Abstracts, 75:86614m (1971).
Chemical Abstracts, 83:26071n (1975).

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