Optics: measuring and testing – For light transmission or absorption – Of photographic film
Patent
1988-03-28
1991-08-06
Rosenberger, Richard A.
Optics: measuring and testing
For light transmission or absorption
Of photographic film
2504581, 356344, 356417, G01J 310
Patent
active
050372076
ABSTRACT:
A laser imaging system is disclosed which provides the versatility of wide field digital imaging with enhanced spatial resolution and light gathering efficiency. The system will scan targets of any size, dependent only upon the data retrieval and storage limitation of the computer support system, for forward light loss densitometry images as well as fluorescent and forward scatter images. The system is easily adaptable for rare event detection and tracking. The laser system will provide image capture of an entire target within 10 to 60 seconds and controls the scan of the laser beam in three-dimensional pattern and speed. The beam may be repositioned to any one of 16 million locations on a target within an accuracy of +/-0.5 um. Finally, the imaging system of the present invention utilizes a novel optical fiber based detector assembly having NA values of 0.58-0.95 and filters having less than 15% loss at emission wavelengths. Thus, the imaging system of the present invention can capture from 14% to 32% of total fluorescence emission.
REFERENCES:
patent: 3450455 (1969-06-01), Landre
patent: 3516746 (1970-06-01), Shibata et al.
patent: 3981590 (1976-09-01), Perkins
patent: 4107534 (1978-08-01), Piltingsrud
patent: 4523799 (1985-06-01), Delhaye
patent: 4586781 (1986-05-01), Gunther et al.
patent: 4758727 (1988-07-01), Tomei et al.
Nicoll, F., "Mural Television Display Using Fiber Optics", RCA Technical Notes (RCA TN No. 188, 1958).
Dyer et al., "Vidicon Microscope for Counting Fluorescent Particles", Review of Scientific Instruments, vol. 24, No. 4 (1971), p. 508.
Slomba et al., "A Laser Flying Spot Scanner for Use in Automated Fluorescence Antibody Instrumentation", Journal of the Association for the Advancement of Medical Instrumentation, vol. 6, No. 3, May-Jun. 1972.
Bussini et al., "A Silicon Rubber Scintillation Compound for Complex Geometry Radiation Detectors", Nuclear Instruments and Methods, No. 2, (1973), pp. 333-335.
"The New FACS 400 Series, FACS 440, FACS 420, FACS 400, Fluorescence Activated Cell Sorting", Becton Dickenson FACS Systems, 1981.
"The FACS Analyzer Fluorescence and Volume Cell Analysis" Brochure, Becton Dickenson FACS Systems, 1982.
Young et al., IEEE Transactions on Biomed. Engineering, BME-29;2, 1983.
Shoemaker et al., IEEE Transactions on Biomed. Engineering, BME-33, 1984.
"Photodigitizing with PDS Microdensitometer Systems" Brochure, Perkin-Elmer, not dated.
"Microdensitometer 3 CS" Brochure, Joyce-Loebl, not dated.
"Microdensitometer 6" Brochure, Joyce-Loebl, not dated.
"EIKONIX.RTM. Applied Research Software and Product Development Feasibility and Impact Studies Automated Instruments" Brochure, EIKONIX.RTM. Corporation, not dated.
"ACAS 470 Workstation" Brochure, Meridian Instruments, Inc., not dated.
"Cytoscan-Cytogenetic Scanning Analyser System" Brochure, Image Recognition Systems, Ltd., not dated.
Chen Inching
Cornhill Fred
Jagadeesh Jogikal
Tomei L. David
Ohio State University Research Foundation
Rosenberger Richard A.
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