Radiant energy – Ionic separation or analysis – With sample supply means
Reexamination Certificate
2007-02-14
2011-12-27
Berman, Jack (Department: 2881)
Radiant energy
Ionic separation or analysis
With sample supply means
C250S282000
Reexamination Certificate
active
08084734
ABSTRACT:
The present invention provides a method of producing a laser-patterned silicon surface, especially silicon wafers for use in laser desorption ionization (LDI-MS) (including MALDI-MS and SELDI-MS), devices containing the same, and methods of testing samples employing the same. The surface is prepared by subjecting a silicon substrate to multiple laser shots from a high-power picosecond or femtosecond laser while in a processing environment, e.g., underwater, and generates a remarkable homogenous microcolumn array capable of providing an improved substrate for LDI-MS.
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Chen Yong
Vertes Akos
Berman Jack
Blank Rome LLP
The George Washington University
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